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One score, and the two groups it separates

Two groups sorted by clinical blood work

Accuracy

14 of 14

Days the Two Groups Stayed Apart

normal glucose control scoring above early dysregulation every day, in groups sorted by clinical blood work

Reference standard

Laboratory blood work

Sample size

105 adults in the published study

Two groups, sorted by clinical blood work and then followed for 14 days: the daily score stayed higher in the group with normal glucose control on every one of the 14 days.

02550751001234567891011121314Normal glucose control, 53 peopleEarly glucose dysregulation, 52 peopleaverage daily Metabolic Score, by group
14 of 14days the healthy group averaged higher
79average score, normal glucose control
74average score, early dysregulation
105adults, sorted into the two groups by blood work
Figure 1 — Each point is a day’s group average from Supplementary Fig. S3; 79 and 74 are means of those points, which the study does not report.
00.250.50.7510.43Insulinresistance0.42Glucosetolerance test0.38Inflammation0.36Long-termglucose controlstrength of the inverse relationship, 0 to 1, in the group with early dysregulation
0.43strength of the link to insulin resistance
0.42to a glucose tolerance test
0.38to inflammation
0.36to long-term glucose control
Figure 2 — A higher score goes with a lower marker on all four. The dashed reference line at 0.40 is how closely height tracks weight in adults, a relationship most people already have a feel for.

Glucose never sits still. Every meal sends it up, every recovery brings it back down, and it is the shape of that rise and fall across a whole day, not the height of any one reading, that describes how well the body is handling fuel. Two people can eat the same plate of food and produce completely different curves, and neither would know it. A fasting number catches one quiet moment of a day that is never quiet, which is why most of glucose control stays invisible without continuous measurement.

The Metabolic Score is the single daily number the Ultrahuman M1 CGM builds from that whole picture: the peaks, the time spent inside a healthy range, and the average underneath. In a research study, 105 adults were sorted by blood work into 53 with normal glucose control and 52 with early glucose dysregulation, then followed for 14 days. The first group averaged about 79, the second about 74, and the two group averages stayed apart on every one of the 14 days.

Against the blood work a clinic would order, the score tracks four separate markers, most strongly insulin resistance at 0.43 — a higher score going with lower resistance — about as tight as the relationship between height and weight. It is built from 14 days of glucose rather than one morning reading, which is what lets it stand in for markers that themselves describe weeks or months — a span no single fasting value can cover.